Rebirth of the God-level Xueba

"The leader is at the front." The young clerk led a few reporters to take a needle, stopped and let out a sigh of relief, and said: "You all have the discipline of interviewing, so I won't say more. Finally, your interview draft today, You must send a copy to Li Ban, and you are allowed to publish it before you publish it."

"It must be obeyed." Director Hong licked his face and smiled.

In terms of rank, the young man in front of him might be the lowest among all the people present. But so what, they have a lot of power, and they can change the TV station's course with a single sentence. Therefore, Director Hong must not only obey orders, but also have a good attitude.

The young clerk was indeed satisfied, nodded, and said, "I won't follow you once you go in. Well, be careful not to interrupt, it's best to ask questions alone. The leader doesn't like people talking too much."

He only added one more sentence because he saw Director Hong's good attitude. Of course, it was to avoid making the leader unhappy.

Director Hong quickly thanked him, and when he walked in, he said in a low voice: "I will ask questions in a while, Wu Qianyang, you are a girl, please interrupt when encountering a situation, other people are not allowed to speak."

The order is arbitrary and effective, and it doesn't make sense, including Kong Yingguang.

"Sales are easy. The most advantageous aspect of rare drugs is that there is less competition. If there are useful drugs on the market, we don't need to develop new ones. Therefore, after our drugs come out, basically Don't worry about competition."

"The second is that the approval process is closed. The most important approval process in foreign countries is the FDA in the United States. After passing their approval, it is much easier to go to the European Union and other countries to apply. In this regard, Zeneca is mainly responsible. We choose them Being an investor also takes into account their conditions..."

"Zeneca is of course very active. The profit of rare drugs is still considerable, and its annual sales volume will not be too large, but it is stable and can basically provide a steady stream of cash flow, which is more reliable than banks. Like us What is being treated now is Gaucher's disease, as long as this disease exists, everyone will use this medicine, there is no way."

"In terms of medical expenses... foreign insurance systems can be used. In addition, domestic prices should also be lowered. The medicines we make ourselves can be sold for as much as we want."

Yang Rui's voice is very penetrating. He also gave lectures to Tsinghua University and Peking University in class.

And what he said immediately caught the attention of the reporters.

It is already a bit attractive to sell new drugs abroad. If the price in foreign countries is high and the price in China is low, it will naturally become more topical.

The leader obviously cared about this very much. When he saw Dong Ce and others coming in, he asked, "Can Northern United Pharmaceuticals lower the price of the drug? I heard that this drug is taken for a long time. If it is given to the patient's family It’s not good to be burdened for a long time.”

Dong Ce was asked such a big question as soon as he entered the door, his head turned quickly, and he said: "The research process of Gaucher's disease is expensive. If we want to reduce the price, we must find a way to supplement domestic income with foreign income."

Northern United Industries is a joint venture, and there is no share or share of Yang Rui in it. Therefore, Dong Ce didn't ask Yang Rui when he answered, and Yang Rui didn't care how Dong Ce distributed the profits.

Anyway, the 15 million US dollars that Yang Rui blocked at the beginning was already higher than the expected income of Northern United Industries for several years. As for their willingness to give up more profits, it has nothing to do with Yang Rui.

Therefore, when Mr. Li looked at Yang Rui, Yang Rui just shrugged his shoulders and said: "The core of medicine lies in product development. We know what kind of compound we want to make to treat diseases. Once a product is developed, the difficulty of production is relatively high." smaller."

Of course, compared with drug development itself, the difficulty of production development is really not worth mentioning.

For example, when Yang Rui was engaged in the production and development of coenzyme Q10, the income he obtained was only one million US dollars, and the total value he created for Zeneca was only a few hundred million yuan, which took many years to realize.

Not so with a new drug, however.

As a rare disease drug, Gaucher's disease has low cost and strict approval. Now it has cost tens of millions. If it wants to go on the market in the future, Zeneca will have to prepare at least tens of millions of dollars.

However, once profits are generated, according to the conditions of foreign markets, several hundred million dollars per year is the minimum, and within two or three years, Zeneca can receive ten times the money invested.

The burden on Northern United Industries is heavy, and it is hard to say how much profit will be left in the end, but the most important thing for a state-owned enterprise is to be happy.

"One medicine can save hundreds of thousands of lives. What you have done is remarkable and important." Mr. Li spoke solemnly, and the reporters who had just arrived frantically took notes.

Director Hong did exactly the same thing. Director, Spring Festival Gala, and the title of working group member were all forgotten by him. Tonight, we are all reporters.

"Thank you Mr. Li for your approval." Yang Rui glanced at the reporters, and instead of saying hello, he said in a somewhat emotional tone: "Actually, some people don't support our medicine for rare diseases and think we should do more. Drugs for the general public. This is actually a problem with the way of thinking. It is not that we do not want to make more popular drugs, but if we find a target for a rare disease, we should also use it. Oh, the target can be understood as, from the gene The crux of a disease identified in the world."

Mr. Li nodded and said, "Paying attention to the vulnerable groups is a part of our work that cannot be ignored."

"To put it bluntly, I think that the development of human beings is inseparable from the protection of vulnerable groups." Yang Rui paused, seeing that Mr. Li's expression seemed to be interested, he continued: "Actually, we humans, from the physical Said, it has been getting weaker, like clothes... Primitive humans don't need it, not only don't need it, but a strong evolution should actually have thick hair, a bit stronger, and it can also be like a bird In the same way, it forms a hollow and waterproof feather inside, so that not only clothes are saved, but also umbrellas are unnecessary.”

Everyone laughed at what Yang Rui said.

Yang Rui also smiled and said: "The result is that our ancestors did the opposite, and the mutation of less hair remained. When it was cold, we took care of ourselves, put on fur or weaved clothes, and used fire to solve the problem. For this reason, We save a lot of energy and have a bigger advantage over the competition.”

"This theory is very fresh." Mr. Li felt a little curious when he heard it, and even had some novelty hunting psychology.

For science, most people are still afraid. If you have a better contact with science popularization, you also think it is a very serious thing.

However, Yang Rui was reborn from the 21st century. In his subconscious mind, anything can be serious or light-hearted.

At this time, he seemed to be chatting, and then said: "Reducing the body's own supply and relying on external supplies to ensure life activities is actually our mainstream. The classic example is vitamins. Long ago, human ancestors were able to The benefits of self-synthesizing vitamins are obvious, and people who can synthesize vitamins by themselves will not get scurvy no matter how long they sail on the sea.”

Scurvy is common knowledge that vitamin C is lacking, and everyone still has it, and everyone finds it interesting.

Yang Rui added: "However, synthesizing vitamins, especially vitamin C, was a great burden for early humans, so the mutants that eventually gain an evolutionary advantage do not need to synthesize vitamin C themselves. Humans. We get our vitamins from plants, and there are a lot of them in raw meat and offal.”

"Gaucher's disease is actually a vitamin-like mutation that prevents people from synthesizing glucocerebrosidase. The only problem is that we can't find glucocerebrosidase in nature." Yang Rui shrugged , said: "It is conceivable that our ancestors also had similar mutations for an infinite number of times before finally passing on the vitamin synthesis syndrome to us."

"In addition to books and buildings, our body itself is now history." Mr. Li's speech raised the height immediately. He became excited as he said it himself, and said: "The development of science is changing with each passing day. Your current work is not only unprecedented, but also restores the history of the ancients. Professor Yang Rui, if you want to write a popular science article, it is best Let ordinary people with primary and middle school level understand, this is not only to popularize science, but also to popularize our history.”

"Yes, I will write the article and submit it when I get back. I am afraid that the publisher will think my writing is poor and I will not pass it." Yang Rui made a joke while agreeing.

Director Hong finally seized the opportunity to speak, and hurriedly said: "Your article, other publishers don't understand it, and when it is sent to CCTV, we must focus on promoting it."

He is still very good at talking, and he only said "the publishing house does not understand" instead of "not approved". This not only saved Yang Rui's face, but also his own unit's face, and naturally indirectly protected his own face.

Yang Rui nodded slightly when he heard Director Hong talking to him.

Director Hong was suddenly agitated, and his body couldn't help trembling with goosebumps, as if being watched by a big leader.

His attitude and feeling at this time are of the same origin as the previous attitude and feeling, seamlessly connected, and there is no contradiction.

Dong Ce also took the time to laugh and said: "Don't listen to Professor Yang's modesty. When he was studying, he had published science fiction articles. I heard that he used that manuscript fee to start his own scientific research. It is very remarkable."

Everyone carried the flowery sedan chair, and everyone naturally let out exclamations of surprise to cooperate.

"Mr. Li, Professor Yang, let's visit the workshop from here..." Dong Ce led the way and continued walking with everyone.

Kong Yingguang anxiously scratched his ears and cheeks. With such a speaking pattern, don't even want to know the news.

The news he wanted to know was naturally what the foreign media wanted.

Kong Yingguang's family knows his family affairs. He is a small reporter from the local media. He didn't come in with people from the big media. He was not welcomed by Yang Rui at all. They are not easy to come by. If you want to ask for some valuable news, it will be too difficult.

However, given the current environment, Yang Rui might be willing to say something more.

Kong Yingguang was a little guilty, but also a little excited. He took two steps forward, like an ordinary reporter, and said, "Professor Yang, I heard that you only have one or two days a month at the North United Pharmaceutical Co., Ltd." , what is your main research direction now?"

In a different environment, he definitely wouldn't ask so directly, but at this moment, he might only have one chance to ask a question, so he simply gave up covering it up.

It is impossible for Yang Rui to know Kong Yingguang. He only thought that he came with Director Hong. He smiled slightly and said, "The current one is still working on cells and genetics. It will take a while for the genetic engineering laboratory to be completed."

Kong Yingguang's guess was very accurate. In another environment, Yang Rui would never say words like "cells and genetics", and he would not even mention the name of the genetic engineering laboratory. Most likely, he would say some negative sentences.

However, with Mr. Li right by his side, how could Yang Rui take the initiative to belittle his work? Even if you don't think about yourself, you have to think about the people in the laboratory. This is almost the natural way of thinking of top students—exploitation must be exploited, and pressure and responsibility must be carried.

In the face of leaders, even those who have no achievements have to blow out some achievements. Wouldn't it be fatal to reverse the operation?

The genetic engineering laboratory is a public laboratory, and it also spends a large amount of funds. The expenditure can be ranked among the top ten domestic scientific research expenditures. It is even more exaggerated in terms of per capita. With so much funds spent, Yang Rui can say, "Even a bubble is too expensive." Didn't it come out?"

However, Yang Rui still refrained from saying "cloned sheep". This is mainly because cloning is too sensitive, and he is even more unwilling to let the leader judge whether it is valuable.

Kong Yingguang silently wrote down Yang Rui's answer, and when he wanted to ask more questions, he was pulled away calmly.

"This is our mouse research base. According to Professor Yang Rui's research, we found that Chinese hamsters are the most suitable for providing glucocerebrosidase. Related research papers have been published in famous journals in Europe and America..." Dong Ce led With a smile, he continued to be a guide.

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